产品货号：
Z16014
中文名称：
DUSP3抗体
英文名称：
Anti-DUSP3 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DUSP3 Antibody |
| 指标别名 | dual specificity phosphatase 3;DUSP3;VHR |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | DUSP3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human VHR. |
| 计算分子量 | 20KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Dual specificity protein phosphatase 3 is an enzyme that in humans is encoded by the DUSP3 gene.It is mapped to 17q21.31.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily.These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK,SAPK/JNK,p38),which are associated with cellular proliferation and differentiation.Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases,different tissue distribution and subcellular localization,and different modes of inducibility of their expression by extracellular stimuli.This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer.Although DUSP3 is expressed in both breast and ovarian tissues,mutation screening in breast cancer pedigrees and in sporadic tumors was negative,leading to the conclusion that this gene is not BRCA1. |
| Uniprot ID | P51452 |
| 基因名全称 | Dual specificity protein phosphatase 3 |
| 蛋白名全称 | Dual specificity protein phosphatase 3 |
| 推荐稀释比 | WB 1:500～1:2000 IHC-P 1:100～300 ELISA 1:20000 |
相关搜索：DUSP3抗体，DUSP3多抗，Anti-DUSP3 Antibody